How does norfluoxetine's half-life compare to Prozac's?

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The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ... Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life. Half-life: 4-6 days (chronic administration); 1-3 days (acute); 7-6 days (cirrhosis). Dialyzable: No. Excretion: Urine (15%). Pharmacogenomics. Several SSRIs ... Sep 10, 2018 ... Fluoxetine has a half-life of 4–6 days, while its metabolite norfluoxetine has a half-life varying from 4 to 16 days. Risperidone is an ... Apr 3, 2023 ... The half-life of Prozac is longer than that of Zoloft. If you miss a dose or stop taking either antidepressant medication abruptly, the effects ... Sertraline (Lustral®) – has a shorter half-life. The long half-life metabolite is only marginally active, unlike that in fluoxetine and hence is unlikely to ... Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant ... "[Pharmacokinetics of SSRI antidepressants: half-life and clinical ... How Long Does it Take For Prozac (Fluoxetine) to work? Because of its long half-life (4 to 6 days), the initial impact arises within two weeks to about a month. Jul 1, 1997 ... ... half-life of fluoxetine and 7- to 9-day half-life of norfluoxetine. Bruising and bleeding disorders have also been described with fluoxetine use ... Of the SSRIs, fluoxetine is generally not recommended for use in the elderly because of its long half-life and prolonged side effects. Paroxetine is also ...
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