What is the effective half-life of Prozac, considering both the parent drug and its active metabolite?

Feb 24, 2022 ... It will take longer to leave the body completely. Specifically, it can take around 25 days or more for Prozac to leave your system. Its mean terminal half–life after a single dose was 8.6 days and after multiple dosing was 9.3 days. Steady–state levels after prolonged dosing are similar to ... Discontinuation symptoms have been reported in association with selective serotonin reuptake inhibitors (SSRIs). Because of the long elimination half-life of ... Jan 17, 2024 ... ... half-life of 24 ± 2 h. However, the biological half-life of both fluoxetine and venlafaxine in the presence of L.stagnalis is unexplored. Sep 12, 2024 ... Serotonin syndrome often resolves within 24 hours of discontinuing the serotonergic agent and initiating care, but drugs with long half-lives or ... It is established that both fluoxetine and norfluoxetine have very long half-lives of 4–6 days and 4–16 days, respectively. Additionally, it has been reported ... When stopping antidepressant medication: - Consider the half-life of the antidepressant - those with a shorter half-life such as venlafaxine and paroxetine ... Many people don't see them until a couple weeks after they've stopped taking Prozac because Prozac has a longer half-life than other antidepressants. As a ... Jun 1, 2016 ... Five half-lives equates to about five days for most SSRIs except fluoxetine, which can still be significantly active five or more weeks after ... Jun 27, 2019 ... These include fluoxetine (aka Prozac), paroxetine (aka Paxil) ... half life of 20-100 hours). These can be highly addictive. These are ...