How does liver function affect Prozac's half-life?

Jun 17, 2014 ... Question: The antidepressant fluoxetine (or Prozac) has a half-life of about 3 days What percentage of a dose remains in the body after a day? The half-life of a medication is relevant to understanding its effects and potential withdrawal symptoms. Fluoxetine has a half-life of approximately 4-6 days. Sep 19, 2023 ... Some have suggested that, for other SSRIs, along with serotonin and norepinephrine reuptake inhibitors (SNRIs) (with much shorter half-lives ... Sep 12, 2024 ... Serotonin syndrome often resolves within 24 hours of discontinuing the serotonergic agent and initiating care, but drugs with long half-lives or ... The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ... Half-life: 4-6 days (chronic administration); 1-3 days (acute); 7-6 days (cirrhosis). Dialyzable: No. Excretion: Urine (15%). Pharmacogenomics. Several SSRIs ... Jan 12, 2024 ... Despite its long-half life, symptoms associated with the discontinuation of PROZAC have been reported in clinical trials and post-marketing ... Discontinuation symptoms have been reported in association with selective serotonin reuptake inhibitors (SSRIs). Because of the long elimination half-life of ... Apr 6, 2023 ... And if you've been taking Prozac for a while, it takes about 4 to 6 days for your body to get rid of just half of it. For most people, it takes ... Oct 1, 2019 ... Percentage remaining after one day: We can use the formula for exponential decay, which is: Remaining Percentage = 100 * (1/2)(time/half-life).