How does the long half-life of Prozac affect its potential to cause hyponatremia?

Apr 24, 2023 ... • Drug half-lives can vary drastically. • Fluoxetine (Prozac) has a half-life of 4-6 days and has an active metabolite (norfluoxetine) that. Feb 19, 2008 ... Fluoxetine, marketed under the brand name Prozac ... The period is longer in the former incidence because of the long half-life of fluoxetine in ... Administering a drug less than once per day is generally not done, however. The ideal antidepressant would have a half-life consistent with once-a-day dosing or ... These studies suggest that fluoxetine has a long half-life, which contributes to its steady presence in the bloodstream, potentially leading to fewer side ... Paroxetine is also troublesome while fluoxetine rarely causes withdrawal symptoms. (especially if the dose is under 40 mg) due to the long half-life of the ... Because fluoxetine and its major metabolite, norfluoxetine, have long half-lives, a 6-week washout inter- val should be observed following discontinuation ... ... fluoxetine's long half-life. (compared to other antidepressants that can be washed out more quickly). ⦁ Also due to long half-life, effects of dose changes ... May 31, 2024 ... Also, fluoxetine has a comparatively longer half-life (48-72 hours compared to 27-33 hours for escitalopram), resulting in a more prolonged ... Feb 24, 2022 ... It will take longer to leave the body completely. Specifically, it can take around 25 days or more for Prozac to leave your system. Sep 17, 2024 ... Although Prozac has a longer half-life than some other SSRIs, meaning it stays in the body longer, suddenly stopping the medication can still ...