Are there any pharmacokinetic interactions to be aware of in patients with narcolepsy?

Sep 24, 2022 ... Furthermore, in rodents, continuous administration of fluoxetine in drinking water corresponds better with the clinical situation since the half ... 1 The half- lives of sertraline and fluoxetine in dogs are 26 and 20 hours, respectively.8 The half-life of paroxetine is 20 hours, but it increases in ... A sensitivity analysis found that removing responses involving fluoxetine, which has an especially long half-life, did not significantly alter this result. The long elimination half-lives of fluoxetine and norfluoxetine assure that, even when dosing is stopped, active drug substance will persist in the body for ... Jan 12, 2024 ... Despite its long-half life, symptoms associated with the discontinuation of PROZAC have been reported in clinical trials and post-marketing ... The half-life of Prozac is about 4 to 16 days. A drug's half-life describes how long it takes for half of a dose to be removed from your body. It typically ... Apr 3, 2023 ... The half-life of Prozac is longer than that of Zoloft. If you miss a dose or stop taking either antidepressant medication abruptly, the effects ... Feb 28, 2024 ... Due to the drug's action on the reuptake of serotonin, fluoxetine produces an activating effect, and due to its long half-life, the initial ... The long half-life of the drug and its metabolite contribute to a 4-week period to reach steady-state concentrations. As with all available antidepressants ... Jun 27, 2019 ... These include fluoxetine (aka Prozac), paroxetine (aka Paxil) ... half life of 20-100 hours). These can be highly addictive. These are ...