What are the limitations of pharmacokinetic models in predicting individual responses to Prozac?

Oct 17, 2013 ... The long elimination half-lives of fluoxetine and its principal metabolite, norfluoxetine, are of potential consequence when medicines are ... Sep 19, 2023 ... Some have suggested that, for other SSRIs, along with serotonin and norepinephrine reuptake inhibitors (SNRIs) (with much shorter half-lives ... A sensitivity analysis found that removing responses involving fluoxetine, which has an especially long half-life, did not significantly alter this result. The half-life of Prozac is initially about one to three days, though with continued use, that extends to four to six days. The drug is 99 percent out of your ... Hepatic. Elimination. Renal. Half-life (fluoxetine): 1–3 days (acute); 4–6 days (chronic) ... Jun 20, 2024 ... Prozac is eliminated from the body slower than all other SSRIs, including Lexapro. This is described by the drug half-life (meaning the time it ... Nov 7, 2022 ... Prozac's half-life is approximately two to six days but can be longer if the patient has used it for a long time. Apr 6, 2023 ... And if you've been taking Prozac for a while, it takes about 4 to 6 days for your body to get rid of just half of it. For most people, it takes ... May 18, 2017 ... ... SSRI paroxetine, has been linked with a small increased risk in birth defects. Fluoxetine has a long half-life, which means it stays longer ... Apr 3, 2023 ... The half-life of Prozac is longer than that of Zoloft. If you miss a dose or stop taking either antidepressant medication abruptly, the effects ...