How can inhibition of CYP enzymes affect Prozac's half-life?

May 3, 2022 ... It has a very long half-life (meaning it takes a long time for it to ... Infant blood levels of fluoxetine may reach more than half of maternal ... Mar 24, 2025 ... Fluoxetine's long half-life is an advantage and a drawback. If fluoxetine works well, an occasional missed dose is not a problem; if problems ... Jun 15, 2024 ... Most SSRIs have a half-life of approximately one day, but Prozac's half-life is four to six days.1 This is important because withdrawal symptoms ... The good effects of fluoxetine may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again. Some ... Aug 12, 2022 ... This long half-life makes it easier to stop fluoxetine than some other antidepressants, which can cause withdrawal symptoms when you stop them ... The half-life of its active metabolite, norfluoxetine, is about 7 to 9 days. Metabolism: Fluoxetine is extensively metabolized in the liver to a desmethyl ... Paroxetine is also troublesome while fluoxetine rarely causes withdrawal symptoms. (especially if the dose is under 40 mg) due to the long half-life of the ... Jun 20, 2024 ... Prozac is eliminated from the body slower than all other SSRIs, including Lexapro. This is described by the drug half-life (meaning the time it ... The half-life of Prozac is initially about one to three days, though with continued use, that extends to four to six days. The drug is 99 percent out of your ... Administering a drug less than once per day is generally not done, however. The ideal antidepressant would have a half-life consistent with once-a-day dosing or ...