Which specific CYP enzymes are involved in Prozac's metabolism?

As most SSRIs have a half-life of around 24 hours, skipping doses creates large changes to drug levels, and so increases the risk and/or severity of withdrawal. Administering a drug less than once per day is generally not done, however. The ideal antidepressant would have a half-life consistent with once-a-day dosing or ... Feb 1, 2001 ... While it is true that fluoxetine's active metabolite has a half-life of up to 16 days, because of its low incidence of side effects compared ... Aug 2, 2022 ... Then wait perhaps 1, 2, or more weeks for things to settle before the next cut. Expect withdrawal symptoms to emerge around the drug's half-life ... Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life. The speed with which a specific antidepressant can be stopped is largely related to its half-life. Agents with very long half-lives, such as fluoxetine (half- ... Apr 7, 2018 ... Brands with a relatively short half-life, like Effexor and Paxil, appear to cause more withdrawal symptoms more quickly than those that stay in ... Mar 6, 2021 ... Pharmacokinetics of Fluoxetine ; Primarily eliminated via hepatic metabolism to inactive metabolites, which are then excreted by the kidney. · 1 ... May 3, 2022 ... It has a very long half-life (meaning it takes a long time for it to ... Infant blood levels of fluoxetine may reach more than half of maternal ... Aug 12, 2022 ... This long half-life makes it easier to stop fluoxetine than some other antidepressants, which can cause withdrawal symptoms when you stop them ...