Are there any pharmacokinetic considerations specific to this patient population?

Sertraline (Lustral®) – has a shorter half-life. The long half-life metabolite is only marginally active, unlike that in fluoxetine and hence is unlikely to ... It is established that both fluoxetine and norfluoxetine have very long half-lives of 4–6 days and 4–16 days, respectively. Additionally, it has been reported ... Withdrawal symptoms (also called antidepressant or SRI discontinuation syndrome) are unpleasant physical and mental effects from reducing the dose of or ... The good effects of fluoxetine may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again. Some ... May 3, 2022 ... It has a very long half-life (meaning it takes a long time for it to ... Infant blood levels of fluoxetine may reach more than half of maternal ... Jun 1, 2016 ... Five half-lives equates to about five days for most SSRIs except fluoxetine, which can still be significantly active five or more weeks after ... Apr 26, 2022 ... Fluoxetine has a half-life of 1–4 days and proved to be effective in the maintenance treatment of major depression and anxiety disorders ... Administering a drug less than once per day is generally not done, however. The ideal antidepressant would have a half-life consistent with once-a-day dosing or ... Further, the elimination half life of it's active metabolite, norfluoxetine, ranges from 4-16 days after both acute and chronic administration. The half-life of ... Apr 6, 2023 ... And if you've been taking Prozac for a while, it takes about 4 to 6 days for your body to get rid of just half of it. For most people, it takes ...