What is the role of active transport mechanisms in the absorption or elimination of Prozac, and how might these processes affect its half-life?

Further, the elimination half life of it's active metabolite, norfluoxetine, ranges from 4-16 days after both acute and chronic administration. The half-life of ... Feb 19, 2008 ... Fluoxetine, marketed under the brand name Prozac ... The period is longer in the former incidence because of the long half-life of fluoxetine in ... The half-life of its active metabolite, norfluoxetine, is about 7 to 9 days. Metabolism: Fluoxetine is extensively metabolized in the liver to a desmethyl ... Mar 6, 2021 ... Pharmacokinetics of Fluoxetine ; Primarily eliminated via hepatic metabolism to inactive metabolites, which are then excreted by the kidney. · 1 ... Jun 27, 2019 ... These include fluoxetine (aka Prozac), paroxetine (aka Paxil) ... half life of 20-100 hours). These can be highly addictive. These are ... ... antidepressant and introducing fluoxetine. Conversely, because of the long half-life of fluoxetine and its metabolite, norfluoxetine, it is recommended that ... According to the FDA, the elimination half-life of fluoxetine is 1 to 3 days after acute administration, and 4 to 6 days after chronic administration, with its ... Apr 3, 2023 ... The half-life of Prozac is longer than that of Zoloft. If you miss a dose or stop taking either antidepressant medication abruptly, the effects ... Jun 25, 2021 ... A randomized placebo-controlled clinical trial suggested that shorter half-life antidepressants may be at higher risk of withdrawal syndrome ... May 18, 2017 ... ... SSRI paroxetine, has been linked with a small increased risk in birth defects. Fluoxetine has a long half-life, which means it stays longer ...