How does the long half-life of Prozac affect the likelihood of neonatal withdrawal syndrome if the mother took Prozac during pregnancy?

A sensitivity analysis found that removing responses involving fluoxetine, which has an especially long half-life, did not significantly alter this result. The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ... How Long Does it Take For Prozac (Fluoxetine) to work? Because of its long half-life (4 to 6 days), the initial impact arises within two weeks to about a month. Feb 28, 2024 ... Due to the drug's action on the reuptake of serotonin, fluoxetine produces an activating effect, and due to its long half-life, the initial ... Jul 1, 1997 ... ... half-life of fluoxetine and 7- to 9-day half-life of norfluoxetine. Bruising and bleeding disorders have also been described with fluoxetine use ... Fluoxetine (brand names: Prozac®, Reconcile®, Sarafem®) is an SSRI (selective serotonin reuptake inhibitor) antidepressant used to treat a variety of ... Feb 1, 2001 ... While it is true that fluoxetine's active metabolite has a half-life of up to 16 days, because of its low incidence of side effects compared ... The speed with which a specific antidepressant can be stopped is largely related to its half-life. Agents with very long half-lives, such as fluoxetine (half- ... Apr 21, 2025 ... Fluoxetine stays in your system longer (with a half-life of 2-7 days, depending on use patterns), resulting in Prozac withdrawal symptoms that ... Jun 27, 2019 ... These include fluoxetine (aka Prozac), paroxetine (aka Paxil) ... half life of 20-100 hours). These can be highly addictive. These are ...