What are the recommendations for Prozac dosage adjustments in patients with hepatic impairment, considering its half-life?

Apr 13, 2025 ... This compound has double the half-life of fluoxetine and has a half-life of anywhere from 4 to 15 days. It can take months for the body to get ... Jun 27, 2018 ... The half-life of Fluoxetine is about 2 to 7 days; however, norfluoxetine lasts longer with a half-life of 4 to 15 days. Fluoxetine stays in the ... May 23, 2022 ... The half-life of a drug is an estimate of the time it takes for the concentration or amount in the body of that drug to be reduced by exactly one-half (50%). Sep 9, 2005 ... Although many women may believe that they are only getting a drug effect during the time they are actually taking fluoxetine, the half life of ... Jan 17, 2017 ... Fluoxetine has unique pharmacokinetic properties, probably what distinguishes fluoxetine from other SSRIs is its long half-life. Most SSRIs have ... Sep 17, 2024 ... Although Prozac has a longer half-life than some other SSRIs, meaning it stays in the body longer, suddenly stopping the medication can still ... Feb 23, 2022 ... Half-life refers to how long it takes for half of the drug to be out of your system (regardless of how much you have in your system right now). Dec 14, 2017 ... Fluoxetine (Prozac), which has a longer half-life compared to ... half-lives. As a result, methylene blue should generally not be given ... The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ... Withdrawal symptoms (also called antidepressant or SRI discontinuation syndrome) are unpleasant physical and mental effects from reducing the dose of or ...