How might liver disease, such as cirrhosis, impact the metabolism and half-life of Prozac?

Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life. Paroxetine is also troublesome while fluoxetine rarely causes withdrawal symptoms. (especially if the dose is under 40 mg) due to the long half-life of the ... Sep 9, 2005 ... Although many women may believe that they are only getting a drug effect during the time they are actually taking fluoxetine, the half life of ... Apr 17, 2023 ... Prozac works by inhibiting the reuptake of serotonin, allowing it to stay in the brain for longer periods and enhancing its effects. Fluoxetine (brand names: Prozac®, Reconcile®, Sarafem®) is an SSRI (selective serotonin reuptake inhibitor) antidepressant used to treat a variety of ... May 31, 2024 ... Also, fluoxetine has a comparatively longer half-life (48-72 hours compared to 27-33 hours for escitalopram), resulting in a more prolonged ... Feb 28, 2024 ... Due to the drug's action on the reuptake of serotonin, fluoxetine produces an activating effect, and due to its long half-life, the initial ... Feb 1, 2001 ... While it is true that fluoxetine's active metabolite has a half-life of up to 16 days, because of its low incidence of side effects compared ... Oct 1, 2019 ... Percentage remaining after one day: We can use the formula for exponential decay, which is: Remaining Percentage = 100 * (1/2)(time/half-life). Hepatic. Elimination. Renal. Half-life (fluoxetine): 1–3 days (acute); 4–6 days (chronic) ...