How does the long half-life of Prozac influence its effects on the menstrual cycle?

Apr 21, 2025 ... Fluoxetine stays in your system longer (with a half-life of 2-7 days, depending on use patterns), resulting in Prozac withdrawal symptoms that ... Sep 9, 2005 ... Although many women may believe that they are only getting a drug effect during the time they are actually taking fluoxetine, the half life of ... The elimination half-life of fluoxetine is 48–72 h, averaging almost 70 h. The half-life of norfluoxetine is 7–9 days. The elimination half-lives for both ... The half-life of a medication is relevant to understanding its effects and potential withdrawal symptoms. Fluoxetine has a half-life of approximately 4-6 days. How Long Does it Take For Prozac (Fluoxetine) to work? Because of its long half-life (4 to 6 days), the initial impact arises within two weeks to about a month. Elimination: The elimination half-life of fluoxetine is 4 to 6 days and for norfluoxetine 4 to 16 days. These long half-lives are responsible for persistence of ... As most SSRIs have a half-life of around 24 hours, skipping doses creates large changes to drug levels, and so increases the risk and/or severity of withdrawal. May 11, 2020 ... ... fluoxetine profile. In fact, due its long half-life and to the time required to induce changes at serotonergic receptor levels, fluoxetine ... According to the FDA, the elimination half-life of fluoxetine is 1 to 3 days after acute administration, and 4 to 6 days after chronic administration, with its ... Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life.