How does the long half-life of Prozac affect its potential to interact with medications used to treat glaucoma?

As might be predicted from its primary site of metabolism, liver impairment can affect the elimination of fluoxetine. The elimination half-life of fluoxetine ... Hepatic. Elimination. Renal. Half-life (fluoxetine): 1–3 days (acute); 4–6 days (chronic) ... Withdrawal symptoms (also called antidepressant or SRI discontinuation syndrome) are unpleasant physical and mental effects from reducing the dose of or ... The long half-life of the drug and its metabolite contribute to a 4-week period to reach steady-state concentrations. As with all available antidepressants ... Apr 24, 2023 ... • Drug half-lives can vary drastically. • Fluoxetine (Prozac) has a half-life of 4-6 days and has an active metabolite (norfluoxetine) that. Elimination: The elimination half-life of fluoxetine is 4 to 6 days and for norfluoxetine 4 to 16 days. These long half-lives are responsible for persistence of ... Sep 9, 2005 ... Although many women may believe that they are only getting a drug effect during the time they are actually taking fluoxetine, the half life of ... The speed with which a specific antidepressant can be stopped is largely related to its half-life. Agents with very long half-lives, such as fluoxetine (half- ... Aug 12, 2022 ... This long half-life makes it easier to stop fluoxetine than some other antidepressants, which can cause withdrawal symptoms when you stop them ... Apr 21, 2025 ... Fluoxetine stays in your system longer (with a half-life of 2-7 days, depending on use patterns), resulting in Prozac withdrawal symptoms that ...