How is telomere length maintained despite the end-replication problem?

Members of the Bcl-2 family play a major role in the patho-biology of head and neck cancer ... cycle and survival of endothelial cells and HNSCC and on the ... Oct 7, 2014 ... ... cells were in G0/G1 phase under physiological conditions (Fig. 1C). There were no significant differences in cell cycle status (G0/G1, S ... The expression of apoptosis-related and cell cycle–related proteins in leukemia cells was analyzed through western blotting. The synergistic effect of the Aza ... Jul 29, 2019 ... Cell cycle analysis. SSCs from the control group and the heat shock-treated group (43 °C, 45 min) were seeded in 6-well plates at ... A cell moves through a series of phases in an orderly manner. During interphase, G1 involves cell growth and protein synthesis, the S phase involves DNA ... S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of ... Jun 26, 2023 ... However, exactly how highly expressed UCP2 regulates cell proliferation, cell cycle, and cell death during the early stage of tumorigenesis has ... A cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends most of its time in what is called interphase. The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK). There are standard modeling algorithms that can then be employed to determine the breakdown of cells in the G0/G1 phase versus S phase, G2, or polyploidy state ...