What happens when replication forks encounter DNA damage or other obstacles, and how are these stalled forks resolved?

Jun 26, 2023 ... However, exactly how highly expressed UCP2 regulates cell proliferation, cell cycle, and cell death during the early stage of tumorigenesis has ... Mar 28, 2018 ... Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells. Dec 26, 2024 ... ... S phase and next cell division event the G2 phase ... phases of the cell cycle but also what specifically occurs during the different phases. Feb 5, 2020 ... The DNA of the cell is doubled during the S phase, and new chromatids are formed. 3) The G2 phase (cell preparation for cell division). During ... Background & Aims: The G1/S-phase controlling mechanism known as the RB pathway is commonly deregulated in human malignancies. Here, the abundance and ... May 10, 2023 ... The S phase of a cell cycle occurs during interphase, before mitosis or meiosis, and is responsible for the synthesis or replication of DNA. Jul 29, 2021 ... Peak Histone Biosynthesis Occurs in Early-to-Mid S Phase. Since cells aligned to anaphase will be partially out of alignment by the time they ... Jan 29, 2020 ... The results showed CMA3 suppressed cell proliferation in vitro in the nM range. At low doses, CMA3 inhibited cell cycle progression at S phase, ... Aug 14, 2008 ... In this study, we show that miR-17-92 is a cell cycle regulated locus, and ectopic expression of a single microRNA (miR-17-5p) is sufficient to ... The expression of apoptosis-related and cell cycle–related proteins in leukemia cells was analyzed through western blotting. The synergistic effect of the Aza ...