What are the metabolic requirements of DNA replication and how is nucleotide synthesis coordinated with the cell cycle?

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DNA Replication. DNA replication occurs in the synthesis or S phase of the Cell Cycle. Every chromosome ... Actively dividing eukaryote cells pass through a series of stages known collectively as the cell cycle: two gap phases (G1 and G2); an S (for synthesis) ... The S phase, occurring between the G1 and G2 phases of the cell cycle, is when DNA replication and much of the DNA repair activity occurs in cells. There are standard modeling algorithms that can then be employed to determine the breakdown of cells in the G0/G1 phase versus S phase, G2, or polyploidy state ... A cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends most of its time in what is called interphase. S phase (Synthesis; when the copying of DNA happens). ... These attack cancer cells during specific phases of the cell cycle, but never during the resting phase. (2010). A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression. PLoS ... S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of ... Oct 25, 2011 ... ... during late mitosis and G to license replication origins for use in S phase. ... cell cycle in Chinese Hamster Ovary (CHO) cells. We find that ... Feb 5, 2020 ... The DNA of the cell is doubled during the S phase, and new chromatids are formed. 3) The G2 phase (cell preparation for cell division). During ...
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