When switching from Prozac to an antidepressant with a shorter half-life, what factors should be considered?

PO, metabolized in the liver primarily by CYP2D6, with fluoxetine (parent drug) having a half life of several day half life of 1-4 days · norfluoxetine is an ... Apr 7, 2018 ... Brands with a relatively short half-life, like Effexor and Paxil, appear to cause more withdrawal symptoms more quickly than those that stay in ... Apr 17, 2023 ... Prozac works by inhibiting the reuptake of serotonin, allowing it to stay in the brain for longer periods and enhancing its effects. Apr 6, 2023 ... And if you've been taking Prozac for a while, it takes about 4 to 6 days for your body to get rid of just half of it. For most people, it takes ... May 9, 2024 ... Side effects of both ... Prozac has a half-life that is longer than Lexapro's, which means it takes longer for Prozac to go through your body. Of the SSRIs, fluoxetine is generally not recommended for use in the elderly because of its long half-life and prolonged side effects. Paroxetine is also ... Jan 5, 2020 ... For many people, antidepressants can be literal lifesavers. But not everyone wants to stay on them indefinitely, and herein lies the problem: ... Sep 9, 2005 ... Although many women may believe that they are only getting a drug effect during the time they are actually taking fluoxetine, the half life of ... Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant ... "[Pharmacokinetics of SSRI antidepressants: half-life and clinical ... 1 The half- lives of sertraline and fluoxetine in dogs are 26 and 20 hours, respectively.8 The half-life of paroxetine is 20 hours, but it increases in ...