What is the relationship between half-life and volume of distribution?

How Long Does it Take For Prozac (Fluoxetine) to work? Because of its long half-life (4 to 6 days), the initial impact arises within two weeks to about a month. Of the SSRIs, fluoxetine is generally not recommended for use in the elderly because of its long half-life and prolonged side effects. Paroxetine is also ... As might be predicted from its primary site of metabolism, liver impairment can affect the elimination of fluoxetine. The elimination half-life of fluoxetine ... Sep 10, 2018 ... Fluoxetine has a half-life of 4–6 days, while its metabolite norfluoxetine has a half-life varying from 4 to 16 days. Risperidone is an ... These studies suggest that fluoxetine has a long half-life, which contributes to its steady presence in the bloodstream, potentially leading to fewer side ... Jun 25, 2021 ... A randomized placebo-controlled clinical trial suggested that shorter half-life antidepressants may be at higher risk of withdrawal syndrome ... Nov 7, 2022 ... Prozac's half-life is approximately two to six days but can be longer if the patient has used it for a long time. Jan 12, 2023 ... Prozac has a half-life that can range from 1-3 days depending on the amount of time the individual was on the drug. Longer-term usage of Prozac ... The half-life of Prozac is about 4 to 16 days. A drug's half-life describes how long it takes for half of a dose to be removed from your body. It typically ... Apr 21, 2025 ... Fluoxetine stays in your system longer (with a half-life of 2-7 days, depending on use patterns), resulting in Prozac withdrawal symptoms that ...