Are there any age-related changes in the activity of CYP enzymes that metabolize Prozac, affecting its half-life in elderly patients?

Sep 16, 2011 ... ... (Prozac), the risk of experiencing symptoms related to a decrease in the medication is low. That's because fluoxetine has a long half-life ... Jun 27, 2018 ... The half-life of Fluoxetine is about 2 to 7 days; however, norfluoxetine lasts longer with a half-life of 4 to 15 days. Fluoxetine stays in the ... The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ... The good effects of fluoxetine may, after a while, improve your sex life as your mood lifts and you become interested in life and relationships again. Some ... In general, manufacturers advise caution (prolonged half-life). Hepatic impairment For fluoxetine. Dose adjustments. Manufacturer advises dose reduction or ... If the drug's half-life is important to you. For example, if you are concerned about withdrawal effects and would prefer a drug with a longer half-life. For ... Jan 12, 2024 ... Despite its long-half life, symptoms associated with the discontinuation of PROZAC have been reported in clinical trials and post-marketing ... Fluoxetine (Prozac) used daily (B). Long half-life; agitation, insomnia, anorexia5. SSRI with shorter half-life (e.g., escitalopram. [Lexapro], sertraline [ ... Feb 1, 2001 ... While it is true that fluoxetine's active metabolite has a half-life of up to 16 days, because of its low incidence of side effects compared ... Fluoxetine (brand names: Prozac®, Reconcile®, Sarafem®) is an SSRI (selective serotonin reuptake inhibitor) antidepressant used to treat a variety of ...