How does the long half-life of Prozac affect its stability and shelf life?

... antidepressant and introducing fluoxetine. Conversely, because of the long half-life of fluoxetine and its metabolite, norfluoxetine, it is recommended that ... Withdrawal symptoms (also called antidepressant or SRI discontinuation syndrome) are unpleasant physical and mental effects from reducing the dose of or ... The long half-life of the drug and its metabolite contribute to a 4-week period to reach steady-state concentrations. As with all available antidepressants ... Discontinuation symptoms have been reported in association with selective serotonin reuptake inhibitors (SSRIs). Because of the long elimination half-life of ... Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life. Its mean terminal half–life after a single dose was 8.6 days and after multiple dosing was 9.3 days. Steady–state levels after prolonged dosing are similar to ... The half-life of Prozac is about 4 to 16 days. A drug's half-life describes how long it takes for half of a dose to be removed from your body. It typically ... 1 The half- lives of sertraline and fluoxetine in dogs are 26 and 20 hours, respectively.8 The half-life of paroxetine is 20 hours, but it increases in ... According to the FDA, the elimination half-life of fluoxetine is 1 to 3 days after acute administration, and 4 to 6 days after chronic administration, with its ... Dec 14, 2017 ... Fluoxetine (Prozac), which has a longer half-life compared to ... half-lives. As a result, methylene blue should generally not be given ...