How does the long half-life of Prozac affect its use in patients with attention-deficit/hyperactivity disorder (ADHD)?

Jan 12, 2023 ... Prozac has a half-life that can range from 1-3 days depending on the amount of time the individual was on the drug. Longer-term usage of Prozac ... Oct 17, 2013 ... The long elimination half-lives of fluoxetine and its principal metabolite, norfluoxetine, are of potential consequence when medicines are ... Flumazenil has a short half-life, so it may need to be repeated. Benzodiazepines should not be used to control CNS excitation, because a paradoxical ... The long half-life of the drug and its metabolite contribute to a 4-week period to reach steady-state concentrations. As with all available antidepressants ... Its mean terminal half–life after a single dose was 8.6 days and after multiple dosing was 9.3 days. Steady–state levels after prolonged dosing are similar to ... Sep 12, 2024 ... Serotonin syndrome often resolves within 24 hours of discontinuing the serotonergic agent and initiating care, but drugs with long half-lives or ... Further, the elimination half life of it's active metabolite, norfluoxetine, ranges from 4-16 days after both acute and chronic administration. The half-life of ... May 3, 2022 ... It has a very long half-life (meaning it takes a long time for it to ... Infant blood levels of fluoxetine may reach more than half of maternal ... ... fluoxetine's long half-life. (compared to other antidepressants that can be washed out more quickly). ⦁ Also due to long half-life, effects of dose changes ... The elimination half-life of fluoxetine is about 1 to 4 days, while that of its metabolite norfluoxetine ranges from 7 to 15 days. Fluoxetine has a nonlinear ...