Are there any specific OTC medications or supplements that should be avoided while taking Prozac due to potential pharmacokinetic interactions affecting half-life or metabolism?

Feb 24, 2022 ... It will take longer to leave the body completely. Specifically, it can take around 25 days or more for Prozac to leave your system. Oct 1, 2019 ... Percentage remaining after one day: We can use the formula for exponential decay, which is: Remaining Percentage = 100 * (1/2)(time/half-life). Oct 17, 2013 ... The long elimination half-lives of fluoxetine and its principal metabolite, norfluoxetine, are of potential consequence when medicines are ... ... antidepressant and introducing fluoxetine. Conversely, because of the long half-life of fluoxetine and its metabolite, norfluoxetine, it is recommended that ... Jun 1, 2016 ... Five half-lives equates to about five days for most SSRIs except fluoxetine, which can still be significantly active five or more weeks after ... As most SSRIs have a half-life of around 24 hours, skipping doses creates large changes to drug levels, and so increases the risk and/or severity of withdrawal. Jul 10, 2001 ... ... SSRI plasma concentration and normalized more slowly, corresponding to the drug plasma half-life of about 10 days. The REM fraction of the ... May 31, 2024 ... Also, fluoxetine has a comparatively longer half-life (48-72 hours compared to 27-33 hours for escitalopram), resulting in a more prolonged ... Sep 10, 2018 ... Fluoxetine has a half-life of 4–6 days, while its metabolite norfluoxetine has a half-life varying from 4 to 16 days. Risperidone is an ... Mar 29, 2025 ... Fluoxetine has a long half-life, which can be a concern in certain patient populations, particularly older adults, due to its potential for ...