What are the specific roles of the different DNA polymerases and accessory factors involved in leading and lagging strand synthesis?

Figure 1: A cell moves through a series of phases in an orderly manner. During interphase, G1 involves cell growth and protein synthesis, the S phase involves ... The somatic cell cycle consists of 3 phases: interphase, m phase, and cytokinesis. ... During S phase, each chromosome is replicated. This produces a ... We have shown that CS exerts an inhibitory effect on the proliferation of MDA-MB-231, MCF-7 and T47D breast cancer cells in a dose and time-dependent manner. S phase (Synthesis; when the copying of DNA happens). ... These attack cancer cells during specific phases of the cell cycle, but never during the resting phase. Two gap phases precede the S and M phases; in G1 the cell prepares for DNA synthesis, and in G2 the cell prepares for the mitotic division that takes place in ... Feb 2, 2025 ... DNA is replicated during S phase. Cell division happens during M phase, which includes mitosis (chromosoma formation and segregation between the ... Oct 7, 2014 ... ... cells were in G0/G1 phase under physiological conditions (Fig. 1C). There were no significant differences in cell cycle status (G0/G1, S ... Actively dividing eukaryote cells pass through a series of stages known collectively as the cell cycle: two gap phases (G1 and G2); an S (for synthesis) ... Jan 29, 2024 ... Metastasis in ovarian cancer typically occurs through three ... induces apoptosis and cell cycle arrest at the S phase in. SKOV-3 ... Jul 29, 2019 ... Cell cycle analysis. SSCs from the control group and the heat shock-treated group (43 °C, 45 min) were seeded in 6-well plates at ...