What are the mechanisms that prevent re-replication of already replicated DNA segments?

... phase become less radiosensitive than they are in other phases of the cell cycle. This paper is only available as a PDF. Keywords. Granulocyte/macrophage ... ... during the S-Phase of the cell cycle. Measurement of DNA synthesis is therefore essential for research in many scientific fields, such as assessing cell ... Furthermore, the cell-cycle phase may directly regulate DNA end resection as resection occurs fastest in S phase and CtIP-dependent resection is upregulated by ... In order to ensure that replication occurs only once per cell cycle, geminin inhibits and destabilizes CDT1 during the S, G2 and M phases. At the metaphase/ ... Two gap phases precede the S and M phases; in G1 the cell prepares for DNA synthesis, and in G2 the cell prepares for the mitotic division that takes place in ... Aug 14, 2008 ... In this study, we show that miR-17-92 is a cell cycle regulated locus, and ectopic expression of a single microRNA (miR-17-5p) is sufficient to ... Oct 7, 2014 ... ... cells were in G0/G1 phase under physiological conditions (Fig. 1C). There were no significant differences in cell cycle status (G0/G1, S ... The 5-bromo-2′-deoxyuridine (BrdU) labeling of cells followed by antibody staining has been the standard method for direct measurement of cells in the ... Cells prepare for DNA replication in S phase by loading MCMs at replication origins in the preceding G1 phase, a process called “origin licensing.” The amount ... DNA is replicated during the S phase of. Mitosis versus meiosis. Before division, the cell is diploid, with two unique sets. Image source: By Gabi Slizewska.