What is the potential of systems biology approaches to integrate the vast amount of data related to the S phase and its role in health and disease?

Dec 4, 2019 ... ... cells are sometimes preferentially lost, the fewer manipulations the better. Etoposide induces apoptosis which results in a S phase cell cycle ... There are standard modeling algorithms that can then be employed to determine the breakdown of cells in the G0/G1 phase versus S phase, G2, or polyploidy state ... Actively dividing eukaryote cells pass through a series of stages known collectively as the cell cycle: two gap phases (G1 and G2); an S (for synthesis) ... Jun 26, 2023 ... However, exactly how highly expressed UCP2 regulates cell proliferation, cell cycle, and cell death during the early stage of tumorigenesis has ... S phase. S stands for Synthesis phase. In this phase, the DNA in the cell is replicated, so that the two daughter cells can each get one ... Oct 25, 2011 ... ... during late mitosis and G to license replication origins for use in S phase. ... cell cycle in Chinese Hamster Ovary (CHO) cells. We find that ... Sep 11, 2017 ... Western blot assay was used to detect the levels of cell cycle and apoptosis related proteins. Xenografts in nude mice were used to evaluate the ... Dec 18, 2006 ... This suppression during S phase is apparently regulated by cell cycle position alone and occurs automatically during each cell cycle. If the ... S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of ... Apr 25, 2013 ... In the S phase (synthesis phase), DNA replication results in the formation of two identical copies of each chromosome—sister chromatids—that are ...