How does trisomy 21 affect the development and function of the prefrontal cortex and executive functions?

Down syndrome is the most frequently occurring chromosomal disorder and the leading cause of intellectual and developmental delay in the US and in the world. Dermatological manifestations of Down syndrome, Trisomy 21 syndrome, Complete trisomy 21 syndrome ... What causes Down syndrome? A cell division error during ... Down syndrome is the most frequent chromosomal cause of mild to moderate intellectual disability, and it occurs in all ethnic and economic groups. The degree of ... This extra genetic material causes the physical features and developmental delays in people with Down syndrome. The features are no different if the extra ... People with Down syndrome died about 28 years younger than the general population. Congenital heart anomalies, comorbidities, low birthweight, and Black and ... Dec 26, 2024 ... Down syndrome is a condition in which a person has an extra copy of chromosome 21. Chromosomes are small "packages" of genes in the body's cells. Aug 5, 2015 ... Down syndrome (DS) is a complex, highly variable disorder that arises from trisomy of chromosome 21. It was one of the first chromosomal ... Jul 16, 2009 ... The research sheds light on the genetic underpinnings of aneuploidy, a condition marked by having an abnormal number of chromosomes. Down syndrome is a genetic condition in which a person has 47 chromosomes instead of the usual 46. Nov 12, 2024 ... Down syndrome results from an unusual cell division involving chromosome 21. This unusual cell division results in an extra partial or full ...