Are there any potential gene therapies for Down syndrome in the future?

Jan 7, 2025 ... This study addresses fundamental questions surrounding otitis media effusion in Down syndrome, identifying DYRK1A as a key gene involved in the condition. What is Down syndrome? Down syndrome is caused by the presence of an extra chromosome number 21 in the cells of the developing baby. What is Down syndrome? Down syndrome is caused by the presence of an extra chromosome number 21 in the cells of the developing baby. Down syndrome is caused by an extra chromosome 21. Down syndrome affects people differently. It causes learning difficulties and health problems. This work underlines a Pcp4-dependent ciliopathy in Down syndrome brain affecting cerebrospinal fluid flow. Depending on the cause and severity, the diagnosis and treatment of a tremor may be done by a primary care provider, a neurologist, and/or a movement disorder ... Apr 26, 2023 ... They found that having a third copy of the gene Dyrk1a and at least three other genes was responsible for changes in development that result in ... Down syndrome is the most common genetic cause of intellectual disability, affecting approximately 1 in every 700 children. It is named for John Langdon Down, ... The main cause of hospitalization was due to pneumonia in 50% of cases, followed by acute respiratory failure in 14%. Sometimes the extra number 21 chromosome or part of it is attached to another chromosome in the egg or sperm. This may cause translocation Down syndrome. This ...