How does the extra chromosome 21 influence the development and function of the cerebellum and motor control?

Jul 17, 2013 ... Scientists have corrected the genetic fault that causes Down's syndrome – albeit in isolated cells – raising the prospect of a radical therapy ... Jul 16, 2009 ... The research sheds light on the genetic underpinnings of aneuploidy, a condition marked by having an abnormal number of chromosomes. This extra genetic material causes the physical features and developmental delays in people with Down syndrome. The features are no different if the extra ... Nov 30, 2020 ... Basic studies to improve understanding of the genetic and biological causes of brain abnormalities that lead to Alzheimer's; Observational ... Mar 8, 2018 ... There's no doubt that an extra copy of chromosome 21 is what causes Down syndrome. There's a lot of doubt, however, over which particular ... Jun 11, 2015 ... The most common cause of having a DS babies is presence extra copy chromosome 21 resulting in trisomy. The other causes can be Robertsonian ... This work underlines a Pcp4-dependent ciliopathy in Down syndrome brain affecting cerebrospinal fluid flow. It's not treatable, no, because it's a genetic disorder that occurs in utero; once born it's too late for the patient. There is no cure, other than aborting a ... Dermatological manifestations of Down syndrome, Trisomy 21 syndrome, Complete trisomy 21 syndrome ... What causes Down syndrome? A cell division error during ... Make an Appointment ... Down syndrome, also known as Trisomy 21, is the most common and readily identifiable chromosomal condition associated with intellectual ...