What are the main protein components of stereocilia?

The stereocilia are simpler, containing only an actin cytoskeleton. Each stereocilium tapers where it inserts into the apical membrane, forming a hinge ... Jun 11, 2013 ... Stereocilia are bundles of bristly projections that extend from the tops of sensory cells, called hair cells, in the inner ear. Each stereocilia ... Male Smpx null mice showed a progressive hearing loss starting from high frequency at the 3rd month. Hearing loss in female mice was milder and occurred later. Aug 5, 2022 ... Within the inner ear is the cochlea, which is lined with tiny hair cells called stereocilia. The stereocilia's job is to convert incoming ... Deflection of the bundle of stereocilia is mechanically responsible for stretching ion pores in the stereocilia, allowing a cation current to pass into the cell ... Jan 25, 2022 ... Bending the stereocilia toward the kinocilium depolarizes the cell and results in increased afferent activity. Bending the stereocilia away from ... Apr 6, 2016 ... ... stereocilia. While functionally very different, the protein complexes that organize microvilli and stereocilia have striking parallels. Both ... ... stereocilia functional architecture and self-renewal. Rzadzinska AK 1 ,. Schneider ME ,. Davies C ,. Riordan GP ,. Kachar B. Author information. Affiliations. 1 ... Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ... Jan 21, 2021 ... Abstract. Inner ear hair cells detect sound-induced displacements and transduce these stimuli into electrical signals in a hair bundle that ...