How can autoimmune processes affect the inner ear and potentially stereocilia?

Abstract. Stereocilia are actin-based protrusions on auditory and vestibular sensory cells that are required for hearing and balance. They convert physical ... Mar 27, 2024 ... Stereocilia ... Structures and types of simple epithelia. ... Stereocilia are cylindrical immotile microvilli found on the apical surfaces of ... Jul 22, 2024 ... We conclude that stereocilia fusion is linked with the failure to maintain cellular proteostasis and with disturbances in stereociliary calcium balance. They are distinct from cilia and microvilli, but are closely related to microvilli. They form single "finger-like" projections that may be branched, with normal ... The stereocilia are simpler, containing only an actin cytoskeleton. Each stereocilium tapers where it inserts into the apical membrane, forming a hinge ... Jan 4, 2021 ... show that ADF/cofilin-1 are recruited to mechanotransducing auditory stereocilia tips, where they increase the availability of F-actin barbed. Jun 11, 2013 ... Stereocilia are bundles of bristly projections that extend from the tops of sensory cells, called hair cells, in the inner ear. Each stereocilia ... Jan 21, 2021 ... Abstract. Inner ear hair cells detect sound-induced displacements and transduce these stimuli into electrical signals in a hair bundle that ... Jul 18, 2022 ... Espins are actin-bundling proteins that have a well-characterized role in stereocilia formation; loss of function mutations in Espin result in ... Answer and Explanation: 1. The main function of the stereocilia exhibited by the epithelial cells of the mucosa of the epididymis is to absorb the fluid ...