How does damage to outer hair cells affect hearing sensitivity?

Apr 13, 2017 ... Because the actin filaments in the stereocilia of hair borders still remain as compact bun- dles, albeit very disordered, there must be an addi-. Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ... These results suggest that regulation of stereocilia length occurs through EPS8 and that CDH23 and PCDH15 regulate stereocilia lengthening beyond their role in ... Jan 4, 2021 ... show that ADF/cofilin-1 are recruited to mechanotransducing auditory stereocilia tips, where they increase the availability of F-actin barbed. Jul 8, 2022 ... Inside the inner ear is the cochlea, which is lined with tiny hair cells called stereocilia. The stereocilia's job is to convert sound waves ... This article obtains the stereocilia movement generated by basilar membrane (BM) vibration based on the positional relationship between the various structures ... Apr 26, 2024 ... Stereocilin is associated with hairlike structures called stereocilia, which project from specialized cells called hair cells in the inner ear. Mar 28, 2017 ... Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' ... You are studying the mechanism by which stereocilia in inner ear hair cells bend and transduce a ... staining reveals that it is located at the base of ... The stereocilia of each hair cell are arranged in a precise geometry. This arrangement is asymmetrical and polarized because the stereocilia are arranged in ...