How do stereocilia regenerate after damage?

Jul 21, 2022 ... Sensorineural Hearing Loss. Inside the inner ear is the cochlea, which is lined with tiny hair cells called stereocilia that convert soundwaves ... This article obtains the stereocilia movement generated by basilar membrane (BM) vibration based on the positional relationship between the various structures ... Apr 21, 2025 ... Cilia are made of microtubules, while stereocilia and microvilli are made of actin filaments. The shortest is microvilli, intermediate height ... Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ... Jan 25, 2016 ... ... stereocilia. While functionally very different, the protein complexes that organize microvilli and stereocilia have striking parallels. Both ... Feb 9, 2022 ... These cells possess stereocilia connected to the tectorial membrane. ... During auditory stimulation, sound waves in the cochlea cause deflection ... Oct 18, 2022 ... Stereocilia movements create an electrical signal that the auditory nerve carries to the brain. But accurately capturing and interpreting the ... We previously reported that CIB2 binds to WHRN and is essential for stereocilia staircase architecture of cochlear hair cells. Here, we refine the ... Jan 4, 2021 ... show that ADF/cofilin-1 are recruited to mechanotransducing auditory stereocilia tips, where they increase the availability of F-actin barbed. They have more stereocilia and long stereocilia relative to kinocilia heights. Tip link tensions show parallel behavior in peripheral columns of the bundle ...