How can open-label trials be used to evaluate the effectiveness of interventions aimed at reducing hospitalizations?

MISSION: A Phase 2, Open-Label Trial to Evaluate Safety of Epcoritamab Monotherapy in Subjects with Relapsed or Refractory Diffuse Large B-Cell Lymphoma and ... A randomised controlled open label trial examining the safety of label-recommended semaglutide 1mg dose escalation vs a slower and flexible titration regimen. Jan 1, 2025 ... This open-label study suggests efficacy and safety of psilocybin in severe TRD and supports further study of psychedelics in this population ... Study protocol; Open access; Published: 23 June 2020. ENG-releasing subdermal implants in postpartum teenagers – an open-label trial study protocol. Nov 2, 2023 ... Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria. Gayle Ross ... Mar 8, 2024 ... This randomized open-label trial aimed to replicate this result in a sample of patients with risk factors for stroke (RFS). METHODS. Twenty ... We describe two randomised trials where blinded outcome assessment was not possible, and discuss the strategies used to reduce the possibility of bias. Addition of primaquine to artemisinin combination treatment did not improve elimination of parasitaemia and prevention of gametocyte carriage. This project is being done to test the combination of Loncastuximab Tesirine along with a drug regimen called DA-EPOCH-R for patients with previously ... Jul 9, 2021 ... Phase 1b open-label trial of afatinib plus Xentuzumab (BI 836845) in patients with EGFR mutation-positive NSCLC after progression on EGFR tyrosine kinase ...