What are the methodological challenges in evaluating complementary and alternative medicine interventions?

Abstract. Purpose: Brentuximab vedotin (BV) is hypothesized to selectively deplete T regulatory cells that express CD30 and resensitize tumors to anti–PD-1 ... Open-Label Trial ... An open-label trial is a type of study where both the participants and the investigators are aware of the treatment being provided. It is ... Aug 3, 2022 ... Methods: In this open-label trial, 31 young people aged 12–25 years with a DSM-5 anxiety disorder and no clinical improvement despite treatment ... An Open-label Trial With Plasma Prekallikrein Oligonucleotide Antisense Therapy To Control Angioedema Attacks In Hereditary Angioedema Patients With Normal C1- ... Jul 31, 2024 ... The main aim is to test how safe and effective the medicine ILUVIEN® (190μg) is for children and adolescents, who have non-infectious ... Sep 17, 2024 ... ... Open-Label Trial in Patients with Newly Diagnosed Oligometastatic Prostate Cancer Starting ADT ... The STAMPEDE2 trial is a phase III, randomized, ... Addition of primaquine to artemisinin combination treatment did not improve elimination of parasitaemia and prevention of gametocyte carriage. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Jan 1, 2025 ... This open-label study suggests efficacy and safety of psilocybin in severe TRD and supports further study of psychedelics in this population ... The objective of this investigation is to assess the efficacy of coenzyme Q10 as a preventive treatment for migraine headaches.