What are the consequences of defects in B cell development or function?

Mar 10, 2021 ... ... switching. Neuritin reduced differentiation of mouse and human GC B cells into plasma cells, downregulated BLIMP-1, and upregulated BCL6. May 28, 2019 ... Because we used to think that T cells were the major problem, DMTs often target those cells. But now we see that drugs targeting B cells are ... Oct 13, 2024 ... Introduction · B cells or B lymphocytes (bursa-derived cells) are essential components of adaptive immune response, primarily responsible for ... Nov 12, 2024 ... Prof.dr. J.H. Veelken Prof.dr. M.A. Navarrete Summary B cells are a type of white blood cell that produce antibodies to fight infections. B-cell lymphoproliferative disorders are conditions in the blood involving uncontrolled growth of white blood cells, also called lymphocytes. These conditions ... This meeting will discuss diverse B cell functions, novel insights into B cell biology, and strategies to exploit B cell function for better health. A lymphocyte is a type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells. Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is ... In this study, we have shown that EAE disease initiation and progression are differentially influenced by the depletion of B cells from mice with otherwise ... Background Evidence suggests that monoclonal B-cell lymphocytosis precedes all chronic lymphocytic leukemia cases, although the molecular mechanisms ...