What are marginal zone B cells?

While B-cells produce antibodies to fight infection, T-cells protect people from getting infected by destroying cancerous and infected cells. B-cells are also ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Apr 21, 2015 ... To date, two models of Breg cell development can be suggested. The first is that Breg cells, similar to thymus-derived Treg cells, are a ... T cells are responsible for cell-mediated immunity. B cells, which mature in the bone marrow, are responsible for antibody-mediated immunity. CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies ... Controversies Conference on Therapies Targeting B Cells in Immune-Mediated Kidney Diseases ... The goal of this KDIGO conference is to review the efficacy and ... Feb 11, 2025 ... Exhausted B cells may reduce flu vaccine effectiveness. Poor flu vaccine responses in people with immature and exhausted memory B cells may ... What is primary mediastinal large B-cell lymphoma? Primary mediastinal large B-cell lymphoma (PMBCL) is a type of non-Hodgkin lymphoma (NHL). It is sometimes ... B-cell acute lymphoblastic leukemia, or B-ALL, is a bone marrow and blood cancer. B-ALL occurs at any age but more commonly in children. Learn more about B Cell Acute Lymphoblastic Leukemia (B ALL) and the treatments and research being pioneered at the OSUCCC – James.