What is junctional diversity in BCRs?

Apr 21, 2015 ... To date, two models of Breg cell development can be suggested. The first is that Breg cells, similar to thymus-derived Treg cells, are a ... Nov 10, 2021 ... Lymphocytes are a type of white blood cells. They play a critical role in keeping us healthy. Without them, we can't survive. Feb 13, 2015 ... The immune system can remember a previously experienced pathogen and can evoke an enhanced response to reinfection that depends on memory lymphocyte ... ... B cells might play a critical role in disease pathogenesis. B cells and their antibodies have undisputed roles in health and disease within the airway ... Apr 3, 2017 ... These immune tolerance mechanisms function at various stages of B cell development. Central tolerance refers to the regulatory mechanisms that ... DLBCL is a common type of fast growing (high grade) NHL. Lymphoma develops when white blood cells called lymphocytes grow out of control. The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens. This meeting will discuss diverse B cell functions, novel insights into B cell biology, and strategies to exploit B cell function for better health. In the article “α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model" by Hussain et al., first published online ... B cells are at the centre of the adaptive humoral immune system and are responsible for mediating the production of antigen-specific immunoglobulin (Ig) ...