How do B cells contribute to the diverse clinical manifestations of SLE?

B-cell lymphoproliferative disorders are conditions in the blood involving uncontrolled growth of white blood cells, also called lymphocytes. These conditions ... Jan 17, 2025 ... Cutaneous B-cell lymphoma is a cancer that starts in the white blood cells and attacks the skin. It often causes a lump or group of lumps on the skin. Rate of New Cases and Deaths per 100,000: The rate of new cases of diffuse large B-cell lymphoma was 5.6 per 100,000 men and women per year. The death rate was ... As a result, VA expanded chronic lymphocytic leukemia to include all chronic B-cell leukemias as related to exposure to Agent Orange or other herbicides during ... Newborns with congenital athymia may develop autoreactive oligoclonal T-cell expansion resulting in a constellation of symptoms (e.g erythroderma and ... Apr 12, 2024 ... Current WHO B cell lymphoma classification features the following major updates (Int J Lab Hematol 2017;39:14): Newly defined high grade B cell lymphomas. Controversies Conference on Therapies Targeting B Cells in Immune-Mediated Kidney Diseases ... The goal of this KDIGO conference is to review the efficacy and ... B-cell acute lymphoblastic leukemia, or B-ALL, is a bone marrow and blood cancer. B-ALL occurs at any age but more commonly in children. ... cells, B cells, and plasma cells secreting pathogenic autoantibodies will be illuminated. The importance of cognate B cell help to autoreactive T cells will ... Oct 11, 2016 ... ... B cells during pathogenic secondary DENV infections is needed. This ... B cells yield plasmablasts and plasma cells (Seifert et al., 2015.