How can we develop more effective strategies for preventing and treating diseases involving B cells?

The finding gives oncologists a new target for developing immunotherapies: double negative memory B cells, so-called because they are negative for two markers. Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... Epigenetics is the study of changes in gene activity that are heritable but not caused by changes in the DNA sequence. By modulating gene activities, ... Oct 13, 2024 ... Introduction · B cells or B lymphocytes (bursa-derived cells) are essential components of adaptive immune response, primarily responsible for ... Sep 11, 2007 ... ... B Cells Is Blocked by BCL6 Gene Alterations in B Cell Lymphoma. Masumichi ... B Cells Is Blocked by BCL6 Gene Alterations in B Cell Lymphoma. Mar 10, 2021 ... ... switching. Neuritin reduced differentiation of mouse and human GC B cells into plasma cells, downregulated BLIMP-1, and upregulated BCL6. While B-cells produce antibodies to fight infection, T-cells protect people from getting infected by destroying cancerous and infected cells. B-cells are also ... abstract. Sputum examination is a useful noninvasive method to study airway inflammation. We investigated the reproducibility and validity of the ... Jun 12, 2024 ... INTRODUCTION. B cell prolymphocytic leukemia (B-PLL) is a very rare B cell neoplasm comprised of so-called prolymphocytes, typically with ... The DURAClone IM B Cell panel allows for identification of late maturation stages of B cells, such as transitional stage, isotype class-switch, naïve and memory ...