How can the principles of open science be applied to B cell research to promote data sharing and collaboration?

Newborns with congenital athymia may develop autoreactive oligoclonal T-cell expansion resulting in a constellation of symptoms (e.g erythroderma and ... Nov 29, 2012 ... CD19 is a biomarker for normal and neoplastic B cells, as well as follicular dendritic cells. CD19 is critically involved in establishing ... B cells are at the centre of the adaptive humoral immune system and are responsible for mediating the production of antigen-specific immunoglobulin (Ig) ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Feb 11, 2025 ... Exhausted B cells may reduce flu vaccine effectiveness. Poor flu vaccine responses in people with immature and exhausted memory B cells may ... A lymphocyte is a type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells. The DURAClone IM B Cell panel allows for identification of late maturation stages of B cells, such as transitional stage, isotype class-switch, naïve and memory ... This type of activation produces memory and plasma B cells. Naïve B cells bind to soluble or membrane bound antigens and internalize the antigen. The B cell ... CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies ... T cells are responsible for cell-mediated immunity. B cells, which mature in the bone marrow, are responsible for antibody-mediated immunity.