



Why do individuals with PKD often develop anemia as kidney function declines?
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what is pkd Informational
- Are there any ethnic or geographic variations in the prevalence or severity of PKD? What are the similarities and differences between PKD and other genetic ciliopathies?
- Why has it been historically difficult to slow the progression of PKD?
- How do kidney cysts lead to kidney damage in PKD? What are the complications of PKD?
- How do mutations in these genes lead to PKD?
- Is PKD a single disease or a group of related conditions? What are the fundamental differences between the two main types of PKD ADPKD and ARPKD at a cellular level?
- Can anti-inflammatory medications potentially slow cyst growth or kidney damage in PKD? What is the role of the primary cilium in the development of PKD?
- What is the genetic basis of PKD?
- What impact have patient advocacy groups had on the field of PKD? What are some of the recent advancements in imaging techniques that are improving our ability to diagnose and monitor PKD?
- Can genetic profiling guide treatment decisions in PKD?
- How does the combination of kidney and liver involvement manifest clinically in ARPKD? At what stage of life do symptoms typically begin to manifest in individuals with ADPKD?
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