how does the template strand influence the sequence of the new DNA strand
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what is a template in dna replication Informational
- how does the cell ensure that the entire genome, representing the complete set of templates, is replicated faithfully in each cell cycle
- what are histone chaperones and how do they assist in the assembly and disassembly of nucleosomes during dna replication along the template
- what are some of the diseases associated with defects in mitochondrial dna replication and template integrity
- what is nucleotide excision repair (NER) and how does it remove bulky lesions that distort the DNA template
- how does the cellular localization of replication proteins change during the cell cycle and how does this relate to the availability of the dna template in different compartments of the nucleus
- what is the role of histone chaperones during dna replication and their interaction with the template
- what is the role of specific histone modifications in regulating the timing and efficiency of dna replication at different regions of the genome, based on the underlying template
- what are the different types of dna polymerases and their specialized roles in replicating different parts of the template or dealing with damage
- what are the different dna polymerases involved in replicating the leading and lagging strand templates in eukaryotes
- what is the role of the cohesin complex in maintaining sister chromatid cohesion and its potential influence on template replication and fork progression
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