



what is the role of specific histone modifications in regulating the timing and efficiency of dna replication at different regions of the genome, based on the underlying template
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what is a template in dna replication Informational
- what are the specific mechanisms that allow replication to bypass certain types of dna damage on the template (translesion synthesis)
- how is the lagging strand template replicated in short discontinuous fragments
- what role does the template strand play in dna replication
- are there specific subnuclear structures or domains that serve as replication factories where multiple replisomes are localized for efficient template processing
- what is the significance of the double-stranded nature of DNA as it relates to providing a reliable template
- how many template strands are involved in dna replication
- how do telomeres protect the ends of linear chromosomes from degradation and incomplete replication of the template
- what are common fragile sites in the human genome and why are they prone to replication stress related to the template
- how are the challenges of replicating the lagging strand template in short Okazaki fragments overcome to produce a continuous daughter strand
- what are the unique challenges faced by organisms living in these extreme environments regarding the stability and replication of their DNA templates
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