What are the opportunities for translating basic germ cell research into clinical applications that improve fertility and prevent genetic diseases?

Germ line refers to the sex cells (eggs and sperm) that sexually reproducing organisms use to pass on their genomes from one generation to the next. Jan 8, 2004 ... We show that embryoid bodies support maturation of the primordial germ cells into haploid male gametes, which when injected into oocytes restore ... Germ cell tumors in the brain can cause the following symptoms: Increased fluid in the brain (hydrocephalus)Hormonal imbalance, including early or delayed ... In many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developing gonads. There, they undergo meiosis, ... "Germ Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Primordial germ cells in the mouse. Mar 1, 2025 ... A group of germ cells grows in a way that's not normal. A tumor forms. This usually happens in an ovary or testicle. 14th biennial meeting on Germ Cells to be held at Cold Spring Harbor Laboratory, Long Island, New York. The Malignant Germ Cell International Consortium brings together the world's leading experts in germ cell tumors, from across the spectrum of cancer research. Jun 12, 2024 ... RESULTS. Germ cell removal affects the life span of N. furzeri in a sex-dependent manner. To investigate the role of germ cells in ...