How can we leverage our knowledge of germ cell biology to develop more effective and safer cancer therapies targeting germ cell tumors?

... germ cell. Germ cells are the cells that make the eggs (ova) in females and the sperm in males. Germ cell tumors (GCTs) are made up of these underdeveloped ... Germ cell tumors in the testes of an adolescent male commonly present as an enlarging, solid mass, which may be painful. Within the ovaries, germ cell tumors ... May 17, 1990 ... We observed 16 cases of hematologic neoplasia associated with mediastinal germ-cell tumors. twenty-eight similar cases have been reported in the literature. Sep 11, 2024 ... Ovarian germ cell tumors: Pathology, epidemiology, clinical manifestations, and diagnosis. View Topic. Share. Font Size. Abstract: In mammalian development, the process of gametogenesis begins with a group of germline precursors known as primordial germ cells (PGCs), ... Germ cell tumors (GCTs) are made up of these underdeveloped cells. These tumors are rare. They may be cancer (malignant) or not cancer (benign). Nov 2, 2022 ... The most common benign form of ovarian germ cell tumor is a mature teratoma. Often called a dermoid cyst, teratomas sometimes contain a mixture ... Provides guidance on controversial issues surrounding the diagnosis, treatment and follow-up of early- and late-stage testicular cancer. Germ cells are used to produce human reproductive sex cells called gametes. Germ cells can either be diploid, or haploid (containing half the diploid chromosome ... Cells on the move: Modulation of guidance cues during germ cell migration. Fly (Austin). 2017;11(3):200–207. PMCID: PMC5552272. Reference Link. 1. Deshpande G ...