How can germ cell research contribute to the development of personalized medicine approaches for reproductive health?

Jan 8, 2004 ... We show that embryoid bodies support maturation of the primordial germ cells into haploid male gametes, which when injected into oocytes restore ... Aging is a complex process affecting the whole organism. However, little is known on how germ stem cells age in non-mammalian vertebrates despite their ... Testicular cancers start in germ cells. These are cells in the testicles that make sperm. These tumors often start in the testicles. Abstract Plethodon cinereus is favorable for a study of the history of the germ line. The germ cells are large, while the gonads are small and show an ... We investigated this phenomenon using live-cell imaging and discovered that ectopic germ cells preferentially induce body-wall muscle to extend cellular ... Most germ cell tumors are treated with chemotherapy along with radiation therapy. Chemotherapy Treatment Radiation therapy Surgery In younger children, extragonadal extracranial germ cell tumors usually occur at birth or in early childhood. Most of these tumors are teratomas in the sacrum ... GSCs divide asymmetrically leading to the formation of a self-renewing GSC and a differentiating cystoblast. The cystoblast then undergoes four rounds of ... Germ cell tumors that develop in the brain or spinal cord are also called CNS (central nervous system) germ cell tumors. Germ Cell Tumor. A germ cell tumor is a benign (noncancerous) or malignant (cancerous) mass that forms from germ cells. Most tumors appear in your ovaries or ...