Are there any pharmacokinetic interactions to be aware of when combining Prozac with gabapentin or pregabalin for RLS?

Feb 1, 2001 ... While it is true that fluoxetine's active metabolite has a half-life of up to 16 days, because of its low incidence of side effects compared ... The half-life of a medication is relevant to understanding its effects and potential withdrawal symptoms. Fluoxetine has a half-life of approximately 4-6 days. The long elimination half-lives of fluoxetine and norfluoxetine assure that, even when dosing is stopped, active drug substance will persist in the body for ... Oct 17, 2013 ... The long elimination half-lives of fluoxetine and its principal metabolite, norfluoxetine, are of potential consequence when medicines are ... Apr 3, 2023 ... The half-life of Prozac is longer than that of Zoloft. If you miss a dose or stop taking either antidepressant medication abruptly, the effects ... Jan 4, 2023 ... ... fluoxetine, while paroxetine is appetite ... Due to its short half-life, paroxetine is not optimal for patients who might miss a dose. Feb 23, 2022 ... Half-life refers to how long it takes for half of the drug to be out of your system (regardless of how much you have in your system right now). Jan 12, 2024 ... Despite its long-half life, symptoms associated with the discontinuation of PROZAC have been reported in clinical trials and post-marketing ... May 3, 2022 ... It has a very long half-life (meaning it takes a long time for it to ... Infant blood levels of fluoxetine may reach more than half of maternal ... Many people don't see them until a couple weeks after they've stopped taking Prozac because Prozac has a longer half-life than other antidepressants. As a ...