Are there any pharmacokinetic interactions to be aware of in patients with OAB?

Half-life: 4-6 days (chronic administration); 1-3 days (acute); 7-6 days (cirrhosis). Dialyzable: No. Excretion: Urine (15%). Pharmacogenomics. Several SSRIs ... As might be predicted from its primary site of metabolism, liver impairment can affect the elimination of fluoxetine. The elimination half-life of fluoxetine ... Jun 15, 2024 ... Most SSRIs have a half-life of approximately one day, but Prozac's half-life is four to six days.1 This is important because withdrawal symptoms ... Feb 17, 2023 ... Fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping as fluoxetine and its active metabolite have a long half-life. Apr 7, 2018 ... Brands with a relatively short half-life, like Effexor and Paxil, appear to cause more withdrawal symptoms more quickly than those that stay in ... If the drug's half-life is important to you. For example, if you are concerned about withdrawal effects and would prefer a drug with a longer half-life. For ... Jul 10, 2001 ... ... SSRI plasma concentration and normalized more slowly, corresponding to the drug plasma half-life of about 10 days. The REM fraction of the ... Sep 19, 2023 ... Some have suggested that, for other SSRIs, along with serotonin and norepinephrine reuptake inhibitors (SNRIs) (with much shorter half-lives ... Apr 17, 2023 ... Prozac works by inhibiting the reuptake of serotonin, allowing it to stay in the brain for longer periods and enhancing its effects. May 18, 2017 ... ... SSRI paroxetine, has been linked with a small increased risk in birth defects. Fluoxetine has a long half-life, which means it stays longer ...